Titer Test for Dogs and Cats
Confirm Core Vaccine Immunity In-Clinic
Fast, Reliable & Cost-Effective
VacciCheck is an in clinic, IgG antibody dot-ELISA-based system for confirmation of core vaccine immunity levels in dogs and cats.
This semi-quantitative antibody titer test determines whether your patients are protected or need re-vaccination, helping you make evidence based vaccination decisions.
Titer Test for Dogs and Cats
Confirm Core Vaccine Immunity In-Clinic Fast, Reliable & Cost-Effective
VacciCheck is an in-clinic, IgG antibody dot-ELISA-based system for confirmation of core vaccine immunity levels in dogs and cats. Diseases treated: CPV,CDV, CAV in dogs and FPLV, FHV, FCV in cats.
Key Benefits of VacciCheck
Portable and easy to use:
- Everything you need is included in the kit.
- Can run one sample at a time or batch up to 12 samples.
- Test for all three core vaccine diseases in one run.
- No special training required.
In-Clinic, Same-Day Results
- Perform antibody titer testing directly in your clinic. No shipping. No delays.
- Results in ~ 23 minutes.
High Sensitivity & Specificity
- Lab-grade accuracy with performance validated against gold standard VN and HI assays.
Minimally Invasive
- Requires only a drop of blood (10μL whole blood or 5μL serum/plasma).
Cost-Effective and Client-Friendly
- Affordable. Lower cost than send-out options. Easy for clients to approve.
Evidence-Based Practice Enhancement
- Enables informed vaccine decisions and builds client trust.
Streamlined Automation Available
- Optional automated accessories (RoboComb+, CombCam, Plate Warmer) reduce hands-on time and eliminate subjective result interpretation for consistent, objective titer testing.
How to Use
1. Collect Sample
Draw only 10 microliters of whole blood or 5 microliters of serum/plasma – minimal stress for your patients.
2. Run the Test
Add the small blood sample to the test comb, follow the 6-step protocol through incubation wells, and develop results in 23 minutes.
3. Read Results
Compare sample spot colors to the reference scale or use automated reading with CombCam for objective interpretation of titer levels.
Training Support: Includes instructional videos, visual reference cards, and comprehensive protocols.
Canine VacciCheck Performance
Virus
Sample Size
Sensitivity
Specificity
Gold Standart Method
Canine Adenovirus CAV
183
96%
90%
Virus Neutralization (VN)
Canine Parvovirus CPV
563
97%
94%
Hemagglu-
tination Inhibition (HI)
Canine Distemper CDV
563
96%
88%
Virus Neutralization (VN)
Egerer, A., Schaefer, Z., & Larson, L. (2022). A point-of-care dot blot ELISA assay for detection of protective antibody against canine adenovirus, canine parvovirus, and canine distemper virus is diagnostically accurate. Journal of the American Veterinary Medical Association
Feline VacciCheck Performance
Virus
Sample Size
Sensitivity
Specificity
Gold Standart Method
Feline Calici Virus FCV
344
90%
91%
Virus Neutralization (VN)
Feline Herpesvirus FHV
344
93%
96%
Virus Neutralization (VN)
Canine Distemper CDV
344
89%
98%
Hemagglu-
tination Inhibition (HI)
Clinical Study conducted in 2011 at The Department of Small Animal Clinical Sciences laboratory and the Maddie’s Shelter Medicine Program, in the College of Veterinary Medicine, University of Florida, and at Cornell University Animal Health Diagnostic Center
Additional Equipment
Automate Your Process
Enhance efficiency and consistency with Biogal’s automated accessories
Automated incubation device designed specifically for VacciCheck and ImmunoComb testing protocols.
Objective digital interpretation of VacciCheck results eliminates subjective reading variations.
Literature
A point-of-care dot blot ELISA assay for detection of protective antibody against canine adenovirus, canine parvovirus, and canine distemper virus is diagnostically accurate
AZIZEH EGERER, BS; ZOIE SCHAEFER, DVM; LAURIE LARSON, DVM
Companion Animal Vaccines and ImmunoDiagnostics Service Laboratory, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin–Madison, Madison, WI
Corresponding author: Dr. Larson Laurie.Larson@wisc.edu
Antibody Testing VS Vaccination Applications in Clinical Practice
RICHARD B. FORD PROFESSOR OF MEDICINE, DIPLOMATE ACVIM AND ACVPM (HON)
Companion Animal Vaccines and ImmunoDiagnostics Service Laboratory, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin–Madison, Madison, WI
Corresponding author: Dr. Larson Laurie.Larson@wisc.edu
Prevalence of Serum Antibody Titers against Core Vaccine Antigens in Italian Dogs
PAOLA DALL’ARA, STEFANIA LUZZI, JARI ZAMBARBIERI, FRANCESCO SERVIDA, LAURA BARBIERI, ROBERTO ROSENTHAL, LAURETTA TURIN, ELENA SCARPARO, AND JOEL FILIPE
Published in Life, MDPI
Corresponding author: Dr. Larson Laurie.Larson@wisc.edu
Long-lived immunity to canine core vaccine antigens in UK dogs as assessed by an in-practice test kit
R. KILLEY, C. MYNORS, R. PEARCE, A. NEIL, A. PRENTIS, AND M. J. DAY
MORETON MORRELL COLLEGE, MORETON MORRELL, WARWICKSHIRE, CV35 9BL, UK
MEDIVET, WATFORD, HERTFORDSHIRE, WD24 7UY, UK
HYDE PARK VETERINARY CENTRE, LONDON, W2 2AE, UK
SCHOOL OF VETERINARY SCIENCES, UNIVERSITY OF BRISTOL, LANGFORD, NORTH SOMERSET, BS40 5DU, UK
Corresponding author email: profmjday@gmail.com
Effect of Aging on the Immune Response to Core Vaccines in Senior and Geriatric Dogs
R. KILLEY, C. MYNORS, R. PEARCE, A. NEIL, A. PRENTIS, AND M. J. DAY
MORETON MORRELL COLLEGE, MORETON MORRELL, WARWICKSHIRE, CV35 9BL, UK
MEDIVET, WATFORD, HERTFORDSHIRE, WD24 7UY, UK
HYDE PARK VETERINARY CENTRE, LONDON, W2 2AE, UK
SCHOOL OF VETERINARY SCIENCES, UNIVERSITY OF BRISTOL, LANGFORD, NORTH SOMERSET, BS40 5DU, UK
Corresponding author email: profmjday@gmail.com
Effect of Aging on the Immune Response to Core Vaccines in Senior and Geriatric Dogs
PAOLA DALL’ARA, STEFANIA LUZZI, LAURETTA TURIN, GIULIA CASTALDELLI, FRANCESCO SERVIDA, AND JOEL FILIPE
Published in Veterinary Sciences, MDPI
Corresponding author email: profmjday@gmail.com
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